About
The Microbiology Division is working on different aspects of parasitic disease concerning host-parasites interaction, identification of new strain, mechanism of drug resistance, new drug targets, mechanism of pathogenesis, development of new diagnostic tool and vaccine candidates search for Leishmaniasis.
- Repository for Leishmania strains and Sera bank
- Parasite and bacterial culture
- Advanced technique for primary isolation of Leishmania parasites from Bone marrow/spleen/skin lesion aspirates
- Excellent microscopic for amastigotes finding in aspirates stained on slide
- Drug sensitivity testing’s
- Evaluation of RDT test kit for leishmaniasis
- Assessment of drug concentration by HPLC
- Department vested by sophisticated instruments such as
- Fluorescence inverted microscope and upright microscope
- BOD, CO2 & Bacteriological Incubator
- Bio-safety Cabinet BSL-II & III
- Gradient PCR, SDS-PAGE & Western blotting system
- ELISA Reader
- HPLC & UHPLC
- Soxhlet, Rotary Evaporator, Lyophilizer
- Cold chain, Cryopreservation
- Basic equipments (-20 & -80 deep Freezers, Water bath, Weight machine, Oven, Autoclave and Cold Centrifuge machine, etc)
- Future plan for expansion of Trading in favour of ICMR by kit testing and providing of Characterized strain on demand
- Sensitive media preparation, Contamination removal, Serum free culture media preparation
- Role of adhesion molecule LFA3, Natural killer cells and natural killer T cells in VL
- Parasite role in resistance
- Arsenic role in Leishmania resistance
- Vector saliva specific proteins useful for Leishmania disease control
- Blocking of parasites specific receptor helpful in anaemia control
- Reported many drug targets in Leishmania parasites
- Assessment of Inflammatory Biomarkers
- Vitamin D in Leishmaniasis
- Phytopharmaceutical and drug formulation
- Parasitic anaemia control
- Role of anti-saliva antibodies in disease control
- Anti-leishmanial Immunomodulator
- Drug Resistance
- LD ENR
- CYP51
Email: chandras.lal@icmr.gov.in