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HOD (Molecular Biology)
-Email: abhik.sen@icmr.gov.in

Dr. Abhik Sen
 
A View of Molecular Lab.
Division of Molecular Biology

       Division of molecular biology is mainly concerned with the study on mechanism of pathogenesis, cell survival, cell death, differential gene expression, in–vitro and in-vivo rRNA processing, drug resistance mechanism, innate and cell mediated immunity and development of diagnostic tools for major protozoan parasite, L. donovani (blood parasite).

 
The Scientific Team
Name Qualification          Designation
Dr. Abhik Sen Ph. D. Scientist-D and HOD
Dr. Kavita Bharti Ph. D. Scientist-B
Mr. Amar Kant Singh L.A -II
Mr. Ranjeet Kumar Technician A
 
The Students Team
Name Qualification          Designation
Dr. Vinod Kumar Ph. D. Young Scientist
Dr. Manas Ranjan Dikhit     Ph. D. Postdoctoral Fellow
Dr. Kumar Abhishek Ph. D. Postdoctoral Fellow
Mr. Ajay Kumar Senior Research Fellow
Mr. Manjay Kumar     Senior Research Fellow
Mr. Md. Taj Shafi Senior Research Fellow
Ms. Tanvir Bamra Senior Research Fellow
Ms. Rimi Mukherjee Ph.D. Scholar
Mr. Vickky Kumar Mahto Ph.D. Scholar (CSIR-JRF)
Ms. Sneha Singh Ph.D. Scholar
Ms. Pretty Kumari Ph.D. Scholar (UGC-JRF)
Ms. Moni Kumari Project - JRF
 
Existing infrastructure: 
1. Fluorescence Activated Cell Sorter 2. DNA Sequencer 3. FPLC
4. DNA Microarray System   5. Elispot Analyzer 6. Real Time PCR
7. Gradient Thermal cycler 8. Fluorescence Microscope 9. Inverted Microscop
10. Spectrofluorimeter 11. Nanodrop 12. ELISA Reader
13. Ultracentrifuge    14. CO2 Incubator 15. Electroporator
16. 2-D Gel Electrophoresis System 17. Chemi Gel Doc. System 18. Lyophiliser
 

Current Research Interests: 

  • Host-Pathogen Interaction
  • Mechanism of Cell survival and Pathogenesis
  • Mechanism of Drug Resistance
  • Survival Mechanism under Stress Condition
  • Innate and Adaptive Immune Response
  • Development of Diagnostic Tools
Majour Achievements :

  • Development of Non-Invasive Diagnostic Tool for Visceral Leishmaniasis.
  • Identification of Role of TLR Mediated Signaling Pathway in Visceral Leishmaniasis
  • Construction of Shotgun Genomic DNA Library of L. donovani fortranscriptomic analysis.
  • Identification of Differentially Expressed Genes in Amastigotes form compared to Promastigote form of L. donovani.
  • Identification of Proteome Changes associated with L. donovani Adaptation to Oxidative and Nitrosative Stress.
  • Explored the Mechanism of Amphotericin-B Resistance of L. donovani and identified Differentially Expressed Genes Associated with it.