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Publication list of Dr. Vahab Ali

Suman SS, Equbal A, Zaidi A, Ansari MY, Singh KP, Singh K, Purkait B, Sahoo GC, Bimal S, Das P and Ali V. Up-regulation of cytosolic tryparedoxin in Amp B resistant isolates of Leishmania donovani and its interaction with cytosolic tryparedoxin peroxidase. Biochimie. 2016; 121: 312-325. doi: 10.1016/j.biochi.2015.12.017. (Epub 2015 Dec 30). 


Zaidi A, Singh KP, Anwar S, Suman SS, Equbal A, Singh K, Dikhit MR, Bimal S, Pandey K, Das P and Ali V. Interaction of frataxin, an iron binding protein, with IscU of Fe-S clusters biogenesis pathway and its upregulation in AmpB resistant Leishmania donovani. Biochimie. 2015; 115: 120-135. doi: 10.1016/j.biochi.2015.05.016. (Epub 2015 May 30).


Mishra V, Kumar A, Ali V, Zhang KY and Nozaki T. Characterization of pH-induced transitions of Entamoeba histolytica D-phosphoglycerate dehydrogenase. Int J Biol Macromol. 2015; 79: 284-289. doi: 10.1016/j.ijbiomac.2015.04.058. (Epub 2015 May 2).


Ansari MY, Equbal A, Dikhit MR, Mansuri R, Rana S, Ali V, Sahoo GC and Das P. Establishment of correlation between in-silico and in-vitro test analysis against Leishmania HGPRT to inhibitors. Int J Biol Macromol. 2015; 83: 78-96. doi: 10.1016/j.ijbiomac.2015.11.051.


Yadav A, Amit A, Chaudhary R, Chandel AS, Mahantesh V, Suman SS, Singh SK, Dikhit MR, Ali V, Rabidas V, Pandey K, Kumar A, Das P and Bimal S. Leishmania donovani: impairment of the cellular immune response against recombinant ornithine decarboxylase protein as a possible evasion strategy of Leishmania in visceral leishmaniasis. Int J Parasitol. 2015; 45(1): 33-42. doi: 10.1016/j.ijpara.2014.08.013. (Epub 2014 Oct 15).


Anwar S, Dikhit MR, Singh KP, Kar RK, Zaidi A, Sahoo GC, Roy AK, Nozaki T, Das P and Ali V. Interaction between Nbp35 and Cfd1 Proteins of Cytosolic Fe-S Cluster Assembly Reveals a Stable Complex Formation in Entamoeba histolytica. PLoS One. 2014; 9(10):e108971. doi: 10.1371/journal.pone.0108971.



Equbal A, Suman SS, Anwar S, Singh KP, Zaidi A, Sardar AH, Das P and Ali V. Stage-dependent expression and up-regulation of trypanothione synthetase in amphotericin B resistant Leishmania donovani. PLoS One. 2014; 9(6): e97600. doi: 10.1371/journal.pone.0097600



Pratap Singh K, Zaidi A, Anwar S, Bimal S, Das P and Ali V. Reactive oxygen species regulates expression of iron-sulfur cluster assembly protein IscS of Leishmania donovani. Free Radic Biol Med. 2014; 75C: 195-209


Amit A, Chaudhary R, Yadav A, Suman SS, Narayan S, Das VN, Pandey K, Singh SK, Singh BK, Ali V, Das P and Bimal S. Evaluation of Leishmania donovani disulfide isomerase as a potential target of cellular immunity against visceral leishmaniasis. Cell Immunol. 2014; 289(1-2): 76-85. doi: 10.1016/j.cellimm.2014.03.011.


Ali V and Nozaki T. Iron-sulphur clusters, their biosynthesis, and biological functions in protozoan parasites. Adv Parasitol. 2013; 83: 1-92. doi: 10.1016/B978-0-12-407705-8.00001-X.


Sardar AH, Kumar S, Kumar A, Purkait B, Das S, Sen A, Kumar M, Sinha KK, Singh D, Equbal A, Ali V and Das P. Proteome changes associated with Leishmania donovani promastigote adaptation to oxidative and nitrosative stresses. J Proteomics, 2013; 81: 185-199. doi: 10.1016/j.jprot.2013.01.011. (Epub 2013 Jan 30).


Mishra V, Kumar A, Ali V, Nozaki T, Zhang KYJ and Bhakuni V. Role of conserved active sit tryptophan-101 in functional activity and stability of phosphoserine aminotransferase from an enteric human parasite. Amino Acids. 2012; 43(1): 483-91. doi: 10.1007/s00726-011-1105-x. ( Epub 2011 Oct 29).


Mishra V, Kumar A, Ali V, Nozaki T, Zhang KY and Bhakuni V. Glu-108 is essential for subunit assembly and dimer stability of D-phosphoglycerate dehydrogenase from Entamoeba histolytica. Mol Biochem Parasitol. 2012; 181(2): 117-124. (Epub 2011 Oct 23).


Mishra V, Kumar A, Ali V, Nozaki T, Zhang KYJ and Bhakuni V. Novel protein-protein interactions between Entamoeba histolytica D-phosphoglycerate dehydrogenase and phosphoserine aminotransferase. Biochimie. 2012; 94(8): 1676-1686. doi: 10.1016/j.biochi.2012.02.028.( Epub 2012 Feb 24).


Mishra V, Ali V, Nozaki T and Bhakuni V. Biophysical characterization of Entamoeba histolytica phosphoserine aminotransferase (EhPSAT): role of cofactor and domains in stability and subunit assembly. Eur Biophys J, 2011; 40(5): 599-610. (Epub 2010 Dec 16).


Mishra V, Kumar A, Ali V, Nozaki T, Zhang KY and Bhakuni V. Glu-108 is essential for subunit assembly and dimer stability of d-phosphoglycerate dehydrogenase from Entamoeba histolytica. Mol Biochem Parasitol, 2011 Oct 23. [Epub ahead of print]


Mishra V, Kumar A, Ali V, Nozaki T, Zhang KY and Bhakuni V. Role of conserved active site tryptophan-101 in functional activity and stability of phosphoserine aminotransferase from an enteric human parasite, Amino Acids, 2011 Oct 29. [Epub ahead of print].


Husain A, Jeelani G, Sato D, Ali V and Nozaki T. Characterization of two isotypes of l-threonine dehydratase from Entamoeba histolytica. Mol Biochem Parasitol .2010; 170(2): 100-104.


Mishra V, Ali V, Nozaki T and Bhakuni V. Entamoeba histolytica Phosphoserine aminotransferase (EhPSAT): insights into the structure-function relationship. BMC Res Notes .2010; 3: 52-59.


Sato D, Kobayashi S, Yasui H, Shibata N, Toru T, Yamamoto M, Tokoro G, Ali V, Soga T, Takeuchi T, Suematsu M and Nozaki T. Cytotoxic effect of amide derivatives of trifluoromethionine against the entric protozoan parasite Entamoeba histolytica. International Journal of Antimicrobial Agents, 2010; 35(1): 56-61.


Jeelani G, Husain A, Sato D, Ali V, Suematsu M, Soga T and Nozaki T. Two atypical L-cysteine-regulated NADPH-dependent oxidoreductases involved in redox maintenance, L-cystine and iron reduction, and metronidazole activation in the enteric protozoan Entamoeba. J Biol Chem. 2010; 285(35): 26889-26899. (Epub 2010 Jun 30).


Husain A, Sato D, Jeelani G, Mi-ichi F, Ali V, Suematsu M, Soga T and Nozaki T. Metabolome analysis revealed increase in S-methylcysteine and phosphatidylisopropanolamine synthesis upon L-cysteine deprivation in the anaerobic protozoan parasite Entamoeba histolytica. J Biol Chem, 2010; 285(50): 39160-39170, (Epub 2010 Oct 5)


Maralikova B, Ali V, Nakada-Tsukui K, Nozaki T, van der Giezen M, Henze K and Tovar J. Bacterial-type oxygen detoxification and iron-sulfur cluster assembly in amoebal relict mitochondria. Cell Microbiol, 2010; 12(3): 331-342. (Epub 2009 Nov 3)


Hussain S, Ali V, Jeelani G and Nozaki T. Isoform-dependent feedback regulation of sarine O-acetyltransferase isoenzymes involved in L-cysteine biosynthesis of Entamoeba histolytica. Molecular & Biochemical Parasitol, 2009; 163: 39-47.


Ali V and Nozaki T. Current therapeutics, their problems, and sulfur-containing-amino-acid metabolism as a novel target against infections by "amitochondriate" protozoan parasites. Clin Microbiol Rev, 2007; 20(1): 164-87.


Clark CG, Alsmark UC, Tazreiter M, Saito-Nakano Y, Ali V, Marion S, Weber C, Mukherjee C, Bruchhaus I, Tannich E, Leippe M, Sicheritz-Ponten T, Foster PG, Samuelson J, Noël CJ, Hirt RP, Embley TM, Gilchrist CA, Mann BJ, Singh U, Ackers JP, Bhattacharya S, Bhattacharya A, Lohia A, Guillén N, Duchêne M, Nozaki T and Hall N. Structure and content of the Entamoeba histolytica genome. Adv Parasitol. 2007; 65: 51-190.


Ali V and Nozaki T. Biochemical and functional characterization of phosphoserine aminotransferase from Entamoeba histolytica, which possesses both phosphorylated and non-phosphorylated serine metabolic pathways. Mol Biochem Parasitol, 2006; 145(1): 71-83, (Epub 2005 Oct 5).


Nozaki T, Ali V and Tokoro M. Sulfur-containing amino acid metabolism in parasitic protozoa. Adv Parasitol, 2005; 60: 1-99.


Nakada-Tsukui K, Saito-Nakano Y, Ali V and Nozaki T. A retromerlike complex is a novel Rab7 effector that is involved in the transport of the virulence factor cysteine protease in the enteric protozoan parasite Entamoeba histolytica. Mol Biol Cell, 2005; 16(11): 5294-5303, (Epub 2005 Aug 24).


Ali V, Shigeta Y, Tokumoto U, Takahashi Y and Nozaki T. An intestinal parasitic protist, Entamoeba histolytica, possesses a non-redundant nitrogen fixation-like system for iron-sulfur cluster assembly under anaerobic conditions. J Biol Chem. 2004; 279(16): 16863-16874, (Epub 2004 Feb 2).


Ali V, Hashimoto T, Shigeta Y and Nozaki T. Molecular and biochemical characterization of D-phosphoglycerate dehydrogenase from Entamoeba histolytica. A unique enteric protozoan parasite that possesses both phosphorylated and nonphosphorylated serine metabolic pathways. Eur J Biochem, 2004; 271(13): 2670-2681.


Ali V, Shigeta Y and Nozaki T. Molecular and structural characterization of NADPH-dependent d-glycerate dehydrogenase from the enteric parasitic protist Entamoeba histolytica. Biochem J, 2003; 375(Pt 3): 729–736.


Chiang SC, Ali V, Huang AL, Chu KY and Tone Lee S. Molecular, cellular and functional characterizations of a novel ICAM-like molecule of the immunoglobulin superfamily from Leishmania mexicana amazonensis. Mol Biochem Parasitol. 2001; 112(2): 263-275.


Bhakuni V, Kulkarni S, Ali V, Singh UK, Levy HB and Maheshwari RK. Immunochemotherapy for Leishmania donovani infection in golden hamsters: combinatorial action of poly ICLC plus L-arginine and sodium stibogluconate (Stibanate). J Interferon Cytokine Res, 1999; 19(10): 1103-1106.



Ali V, Prakash K, Kulkarni S, Ahmad A, Madhusudan KP and Bhakuni V. 8-anilino-1-naphthalene sulfonic acid (ANS) induces folding of acid unfolded cytochrome c to molten globule state as a result of electrostatic interactions. Biochemistry, 1999; 38(41): 13635-13642.


Singha UK, Bhakuni V, Ali V and Roy R. Leishmania donovani: metabolite mapping of promastigotes using proton nuclear magnetic resonance spectroscopy. Mol Cell Biochem, 1996; 162(1): 17-22.


Roy R, Mishra PK, Ali V, and Bhakuni V. Metabolic mapping in extract of biological system by HNMR: Comparison of solvent suppression by various two dimensional NMR method. Proc Nat Acad Sci India, 1995; 66: 97-110.



Ali V, Mehrotra S, Singha UK and BHakuni V. Isolation, purification of lipophosphoglycan from leishmania donovani promastigotes of non-pathogenic strain and its in vitro efficacy in protecting against Leishmania donovani infection. J Parasitic Dis, 1995; 19: 153-158.