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HOD (Molecular Biology)
Email: diroffice@icmr.org.in
Ph.: +91-612-2635456
Fax: +91-612-2634379

Dr. Pradeep Das, Director
 
A View of Molecular Lab.
Division of Molecular Biology

       Division of molecular biology is mainly concerned with the study on mechanism of pathogenesis, cell survival, cell death, differential gene expression, in–vitro and in-vivo rRNA processing, drug resistance mechanism, innate and cell mediated immunity and development of diagnostic tools for major protozoan parasite, L. donovani (blood parasite).

 
The Scientific Team
Name Qualification          Designation
Dr. Pradeep Das Ph. D., FNASc, FNA Scientist-G & Director
Mr. Ashish Kumar M.Sc. Research Scientist
 
The Students Team
Name Qualification          Designation
Mr. Abul hasan Sardar M.Sc. (Microbiology) Senior Research Fellow
Mr. Bidyut Purkait     M.Sc. (Biotechnology) Junior Research Fellow
Mr. Ayan Kumar Ghosh M.Sc. (Biochemistry) Ph.D. Scholar
Mr. Abhishek Mandal M.Sc. (Biochemistry) Ph.D. Scholar
Mr. Kumar Abhishek     M.Sc. (Microbiology) Ph.D. Scholar
Ms. Ruby Singh M.Sc. (Biotechnology) Ph.D. Scholar
Ms. Savita Saini M. Sc.-Biotechnology Ph. D. Scholar
Ms. Sudha Verma M. Sc.-Biotechnology Junior Research Fellow
Mr. Ajay Kumar M. Sc.-Biotechnology Junior Research Fellow
 
Existing infrastructure: 
1. Fluorescence Activated Cell Sorter 2. DNA Sequencer 3. FPLC
4. DNA Microarray System   5. Elispot Analyzer 6. Real Time PCR
7. Gradient Thermal cycler 8. Fluorescence Microscope 9. Inverted Microscop
10. Spectrofluorimeter 11. Nanodrop 12. ELISA Reader
13. Ultracentrifuge    14. CO2 Incubator 15. Electroporator
16. 2-D Gel Electrophoresis System 17. Chemi Gel Doc. System 18. Lyophiliser
 

Current Research Interests: 

  • Host-Pathogen Interaction
  • Mechanism of Cell survival and Pathogenesis
  • Mechanism of Drug Resistance
  • Survival Mechanism under Stress Condition
  • Innate and Adaptive Immune Response
  • Development of Diagnostic Tools
Majour Achievements :

  • Development of Non-Invasive Diagnostic Tool for Visceral Leishmaniasis.
  • Identification of Role of TLR Mediated Signaling Pathway in Visceral Leishmaniasis
  • Construction of Shotgun Genomic DNA Library of L. donovani fortranscriptomic analysis.
  • Identification of Differentially Expressed Genes in Amastigotes form compared to Promastigote form of L. donovani.
  • Identification of Proteome Changes associated with L. donovani Adaptation to Oxidative and Nitrosative Stress.
  • Explored the Mechanism of Amphotericin-B Resistance of L. donovani and identified Differentially Expressed Genes Associated with it.